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The depersonalised character of traditional diagnoses allowed the sufferer to objectify the condition as something ‘out there’ cheap 50 mg zoloft amex, perhaps a somewhat forced abstraction, but one with some pragmatic value. By contrast, a diagnosis like ‘chronic fatigue syndrome’, or ‘ME’, is inescapably personal and subjective in character. Every sufferer exhibits a different range of symptoms, and there is no way of objectively confirming or monitoring the course of the illness (Wessely 1998). The net effect of the dramatic expansion in the range of psychiatric diagnosis is that, instead of conferring strength on the patient, bestowing any such label is more likely to intensify and prolong incapacity. The proliferation of diagnoses and the tendency to apply them to ever wider sections of the population reflects a profound demoralisation of society and a deep crisis of subjectivity. Hooked on addiction Over the past decade a sense of heightened individual vulnerability in society has fostered a climate in which people are more and more inclined to attribute responsibility for their behaviour to someone— or something—outside themselves. Thus adults attribute their difficulties in relationships to emotional traumas inflicted on them in early childhood by their parents, students blame their teachers for their poor performance in exams, everybody seeks compensation from somebody else for their misfortunes. In this climate, the concept of addiction, that ‘a substance or activity can produce a compulsion to act that is beyond the individual’s self control’ has a powerful resonance (Peele 1985:xi). As sociologist Frank Furedi puts it, ‘the ideal of the self-determining individual has given way to a more diminished interpretation of subjectivity and the pathology of addiction provides a new standard for determining behaviour’ (Furedi, forthcoming). Alcoholism provides the model of a disease defined by uncontrollable behaviour which can readily be adapted to other activities deemed to be compulsive. The American critic of addiction Stanton Peele observes that ‘there are an awful lot of things that 107 THE EXPANSION OF HEALTH people do that they know they shouldn’t or that they regret doing more of than they want to’. However, ‘once this pattern has been defined as a disease, almost anything can be treated as a medical problem’ (Peele 1995:117). Whereas the struggle to medicalise alcoholism raged for more than a century, the extension of the disease model of addiction, first from alcohol to heroin and tobacco, and then to gambling, shopping and sex has taken place over only a few years. Though there were attempts to advance a disease theory of alcoholism from the end of the eighteenth century, the medical model made little headway against the powerful forces of religion and temperance until after the Second World War (Murphy 1996). During this period the conception of excessive drinking as a moral problem, as a vice demanding punishment, remained ascendant over the notion of alcoholism as a disease requiring treatment. It was not until the 1950s and 1960s, as the influence of religion declined and that of medicine increased, that the ‘disease concept of alcoholism’ gradually gained acceptance (Jellinek 1960).

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Between outbreaks discount 50 mg zoloft otc, Yersinia pestis infects rodents without Conclusive evidence that the loss of PrPC function con- causing much illness. Thus, the rodents become a reservoir of tributes to prion diseases requires further experiments, possi- the infection. What is certain is that the next few Symptoms of infection in humans begin within days years will be crucial and exciting in deducing whether brain after contamination with the plague bacterium. The bacteria metal abnormalities constitute a mechanism in the develop- enter the bloodstream and travels to various organs (e. Symptoms See also BSE and CJD: Socio-economic impact and ethical include shivering, nausea with vomiting, headache, intoler- issues; BSE and CJD; Slow virus and viral diseases ance to light, and a whitish-appearing tongue. If the infection is untreated, the death rate in humans Bubonic plagueBUBONIC PLAGUE approaches 75%. Prompt treatment most often leads to full recovery and a life-long immunity from further infection. Bubonic plague is a disease that is typically passed from Prevention is possible, since a vaccine is available. The flea acquires the bacterium that causes the disease as it lives Unfortunately, the vaccine is protective for only a few months. Humans can also acquire the disease Use of the vaccine is usually reserved for those who will be at by direct contact with infected tissue. The bacterium is called high risk for acquiring the bacterial infection (e. Such use of bacterial infection produces a painful swelling of the lymph antibiotics should be stopped once the risk of infection is nodes. Often the first swelling is evi- gone, to avoid the development of resistance in other bacteria dent in the groin.

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The bacteria cre- or for the extraction of a particular form of cell known as the ate their food using inorganic sulfur compounds gushing out stem cell buy cheap zoloft 25mg on line. These bacteria take in carbon dioxide and ual to maintain his/her blood in the event of a future mishap. Some scientists assert that these unique bacteria with blood screening technologies there are still several hun- should be classified in their own new taxonomic kingdom. From an immunological viewpoint, See also Bacterial kingdoms; Biogeochemical cycles; another reason for autologous banking is that autologous Extremophiles blood will be immunologically identical to the blood present at the time of return transfusion. This eliminates the possibil- ity of an immune reaction to blood that is antigenically differ- AVERY, OSWALD THEODORE (1877-1955) Avery, Oswald Theodore ent from the individual’s own blood. Canadian-born American immunologist The autologous blood collected from the umbilical cord is a source of stem cells. Stem cells are cells that have not yet Oswald Avery was one of the founding fathers of immuno- undergone differentiation into the myriad of cell types that chemistry (the study of the chemical aspects of immunology) exist in the body (e. His studies of the Pneumococcus virus (causing acute under appropriate conditions, stem cells can be encouraged to pneumonia) led to further classification of the virus into many differentiate into whatever target cell is desired. Although this distinct types and the eventual identification of the chemical reality has not yet been fully realized, the potential of stem differences among various pneumococci viral strains. His cell technology as a therapy for various diseases has been work on capsular polysaccharides and their role in determin- demonstrated. These studies also contributed to The differences in blood cells between individuals due to the the development of therapeutic sera used to treat the pneumo- so-called major histocompatibility antigen is not as pronounced nia virus. Thus, umbilical cord blood cells and tissue ogy was the identification of complex carbohydrates as can be used for donation and transplantation. In addition, cord playing an important role in many immunological processes. See also Antibody and antigen; Histocompatibility; Immunity, This discovery forced geneticists of that time to reevaluate cell mediated their emphasis on the protein as the major means of transmit- ting hereditary information. This new focus on DNA led to James Watson and Francis Crick’s model of DNA in 1952 and Autotrophic bacteriaAUTOTROPHIC BACTERIA an eventual revolution in understanding the mechanisms of heredity at the molecular level.

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